SCHEMBL286557

SCHEMBL286557

OCCc1ccccc1Br

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.60
IDO1 P14902 2/20 0.46
GPR52 Q9Y2T5 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 1/20 0.39
CYP2A13 Q16696 1/20 0.38
ALDH1A1 P00352 2/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
PYCR1 P32322 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
RIPK1 Q13546 1/20 0.37
PARP10 Q53GL7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29590438 1.00 TAAR1 (0.60) TAAR1IDO1GPR52TDP1TSHR
Phosphine SCHEMBL8416873 0.98 TAAR1 (0.58) TAAR1IDO1GPR52TDP1TSHR
SCHEMBL4119364 0.88 TAAR1 (0.48) TAAR1IDO1GPR52TDP1TSHR
SCHEMBL534245 0.86 TAAR1 (0.56) TAAR1IDO1GPR52TSHRCYP2A13
SCHEMBL30769022 0.86 TAAR1 (0.56) TAAR1IDO1GPR52TSHRCYP2A13
SCHEMBL3028718 0.84 TAAR1 (0.54) TAAR1IDO1GPR52TSHRALDH1A1
SCHEMBL29351396 0.84 TAAR1 (0.71) TAAR1IDO1GPR52TSHRCYP2A13
SCHEMBL6738136 0.84 TAAR1 (0.71) TAAR1IDO1GPR52TSHRCYP2A13
SCHEMBL9026542 0.82 TAAR1 (0.52) TAAR1IDO1GPR52TSHRALDH1A1
SCHEMBL22288310 0.81 TAAR1 (0.40) TAAR1IDO1GPR52TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 823 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772063-B Preparation process and method of chloro (bromo) styrene 中国科学院大连化学物理研究所 2025-04-29 CN claimed
CN-116023231-A Method for preparing chloro (bromo) styrene by dehydration of chloro (bromo) phenethyl alcohol 中国科学院大连化学物理研究所 2023-04-28 CN claimed
CN-115772063-A Preparation process and method of chloro (bromo) styrene 中国科学院大连化学物理研究所 2023-03-10 CN claimed
CN-115557836-A Preparation method of carboxylic acid 云南大学 2023-01-03 CN claimed
CN-113333018-A Preparation method and application of supported catalyst for preparing halogenated styrene 中触媒新材料股份有限公司 2021-09-03 CN claimed
CN-111233908-A Benzoxaborol-1-ol compound and preparation method and application thereof 南京农业大学 2020-06-05 CN claimed
CN-107857702-A A kind of preparation method of bilastine intermediate 重庆华邦制药有限公司 2018-03-30 CN claimed
WO-2013102935-A2 Cu-MEDIATED ANNULATION FOR THE EFFECTIVE SYNTHESIS OF 3-SUBSTITUTED PHTHALIDES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-07-11 WO claimed
CN-101565679-B Rhodotorula cell and method for producing optical active alcohols by asymmetric conversion UNIV CHINA PHARMA 2013-05-08 CN claimed
CN-101565679-A Rhodotorula cell and method for producing optical active alcohols by asymmetric conversion UNIV CHINA PHARMA (CN) 2009-10-28 CN claimed
EP-1542672-A4 R-BAMBUTEROL, ITS PREPARATION AND THERAPEUTIC USES CHENG J L (US) 2006-06-07 EP claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-1542672-A2 R-BAMBUTEROL, ITS PREPARATION AND THERAPEUTIC USES Cheng, J. L. (US) 2005-06-22 EP claimed
WO-2004014290-A2 R-BAMBUTEROL, ITS PREPARATION AND THERAPEUTIC USES CHENG J L (US) 2004-02-19 WO claimed
US-12630566-B2 KRas G12D inhibitors Mirati Therapeutics, Inc. (US) 2026-05-19 US disclosed
US-20260103454-A1 MODULATORS OF HEMOGLOBIN GLOBAL BLOOD THERAPEUTICS INC (US) 2026-04-16 US disclosed
US-3980722-A Production of bromostyrene, dibromostyrene and alkyl bromides YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1976-09-14 US disclosed
US-3966831-A Production of bromostyrenes YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1976-06-29 US disclosed
US-3957787-A CENTRAL NERVOUS SYSTEM STIMULANTS, MUSCLE RELAXANTS E. R. SQUIBB & SONS, INC. (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630566-B2 KRas G12D inhibitors KRAS, NRAS, HRAS TAAR1 4774/4885IDO1 4512/4885GPR52 1643/4885
US-20260103454-A1 MODULATORS OF HEMOGLOBIN HBZ, HBB, HBG2 TAAR1 2113/4885IDO1 2695/4885GPR52 4329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.