Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415887 | 1.00 | LPAR3 (0.37) | LPAR3LPAR1LPAR2CES2NAAA | |
| SCHEMBL8416925 | 0.72 | LPAR3 (0.38) | LPAR3LPAR1LPAR2CES2NAAA | |
| SCHEMBL8416882 | 0.72 | LPAR3 (0.38) | LPAR3LPAR1LPAR2CES2NAAA | |
| SCHEMBL8413985 | 0.72 | LPAR3 (0.38) | LPAR3LPAR1LPAR2CES2NAAA | |
| SCHEMBL8416960 | 0.72 | LPAR3 (0.38) | LPAR3LPAR1LPAR2CES2NAAA | |
| SCHEMBL8415907 | 0.71 | LPAR3 (0.37) | LPAR3LPAR1LPAR2CES2NAAA | |
| SCHEMBL8415252 | 0.71 | LPAR3 (0.37) | LPAR3LPAR1LPAR2CES2NAAA | |
| SCHEMBL5430404 | 0.68 | ALDH1A1 (0.34) | LPAR3LPAR1LPAR2TSHRHPGD | |
| SCHEMBL5328976 | 0.67 | LPAR3 (0.47) | LPAR3LPAR1LPAR2CES2NAAA | |
| SCHEMBL7949874 | 0.67 | LPAR3 (0.50) | LPAR3LPAR1LPAR2CES2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958906-A | Phospholipid derivatives containing higher elements of the fifth main group | ASTA-MEDICA AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |