Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417362 | 0.88 | TTPA (0.57) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL8418241 | 0.88 | PTGS1 (0.53) | TTPAALDH1A1 | |
| SCHEMBL7826804 | 0.84 | TTPA (0.54) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL8540817 | 0.81 | TTPA (0.50) | TTPAALOX5KMT2AMEN1CACNA1B | |
| SCHEMBL7836352 | 0.80 | TTPA (0.56) | TTPAALOX5KMT2AMEN1ALDH1A1 | |
| SCHEMBL9312772 | 0.79 | TTPA (0.76) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL7825046 | 0.79 | TTPA (0.56) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL2059270 | 0.77 | TTPA (0.67) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL7825923 | 0.77 | TTPA (0.55) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL7836231 | 0.77 | TTPA (0.55) | TTPAALOX5KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889045-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |