Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA3 | P07451 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | CA6 | P23280 | 3/20 | 0.35 |
| ▸ | CA5A | P35218 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15594 | 0.94 | CHRM2 (0.77) | CHRM2TDP1CYP2C9CYP2C19NFKB1 | |
| SCHEMBL11587714 | 0.94 | CHRM2 (0.77) | CHRM2TDP1CYP2C9CYP2C19NFKB1 | |
| SCHEMBL4805968 | 0.90 | CHRM2 (0.72) | CHRM2TDP1CYP2C9CYP2C19NFKB1 | |
| SCHEMBL13703903 | 0.90 | CHRM2 (0.72) | CHRM2TDP1CYP2C9CYP2C19NFKB1 | |
| SCHEMBL10045281 | 0.90 | CHRM2 (0.72) | CHRM2TDP1CYP2C9CYP2C19NFKB1 | |
| SCHEMBL25443482 | 0.90 | CHRM2 (0.72) | CHRM2TDP1CYP2C9CYP2C19NFKB1 | |
| SCHEMBL8736488 | 0.90 | CHRM2 (0.82) | CHRM2TDP1CYP2C9CYP2C19NFKB1 | |
| SCHEMBL11434663 | 0.88 | CHRM2 (0.68) | CHRM2TDP1CYP2C9CYP2C19NFKB1 | |
| SCHEMBL8355339 | 0.88 | CHRM2 (0.88) | CHRM2TDP1NFKB1CA12CA2 | |
| SCHEMBL902505 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965434-A | COMPOUNDS CONTAIN CATIONIC GROUPS WHOSE POSITIVE CHARGE INCREASES WITH DECREASING PH; CATIONIC LIPOSOMES FUSE AT PH'S IN THE LOW END OF THE PHYSIOLOGIC RANGE; USE IN DRUG DELIVERY SYSTEMS; EFFICIENCY, LESS TOXICITY | FUGENT, LLC | 1999-10-12 | — | — | US | disclosed |