SCHEMBL10045281

SCHEMBL10045281

CN(CCCN)CCCN(C)CCCN

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.72
TDP1 Q9NUW8 1/20 0.40
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NFKB1 P19838 1/20 0.38
CA12 O43570 3/20 0.37
CA2 P00918 3/20 0.37
CA3 P07451 3/20 0.37
CA4 P22748 3/20 0.37
CA6 P23280 3/20 0.37
CA5A P35218 3/20 0.37
CA7 P43166 3/20 0.37
CA9 Q16790 3/20 0.37
CA14 Q9ULX7 3/20 0.37
CA5B Q9Y2D0 3/20 0.37
DNM1 Q05193 4/20 0.35
CA1 P00915 2/20 0.35
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13703903 1.00 CHRM2 (0.72) CHRM2TDP1CYP2C9CYP2C19NFKB1
SCHEMBL11587714 0.97 CHRM2 (0.77) CHRM2TDP1CYP2C9CYP2C19NFKB1
SCHEMBL15594 0.97 CHRM2 (0.77) CHRM2TDP1CYP2C9CYP2C19NFKB1
SCHEMBL4805968 0.93 CHRM2 (0.72) CHRM2TDP1CYP2C9CYP2C19NFKB1
SCHEMBL8736488 0.93 CHRM2 (0.82) CHRM2TDP1CYP2C9CYP2C19NFKB1
SCHEMBL25443482 0.93 CHRM2 (0.72) CHRM2TDP1CYP2C9CYP2C19NFKB1
SCHEMBL12946143 0.91 CHRM2 (0.62) CHRM2TDP1CYP2C9CYP2C19NFKB1
SCHEMBL2979957 0.91 CHRM2 (0.62) CHRM2TDP1CYP2C9CYP2C19NFKB1
SCHEMBL12946136 0.91 CHRM2 (0.62) CHRM2TDP1CYP2C9CYP2C19NFKB1
Hydroxyamine SCHEMBL8417352 0.90 CHRM2 (0.68) CHRM2TDP1CYP2C9CYP2C19NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801262-A Leveling agent, electroplating composition and application thereof 华为技术有限公司 2024-04-02 CN disclosed
WO-2024061290-A1 LEVELING AGENT, ELECTROPLATING COMPOSITION, AND USE THEREOF 华为技术有限公司 2024-03-28 WO disclosed
US-8148577-B2 Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors THE JOHNS HOPKINS UNIVERSITY (US) 2012-04-03 US disclosed
US-20110092601-A1 LYSINE-SPECIFIC DEMETHYLASE INHIBITORS THE JOHNS HOPKINS UNIVERSITY (US) 2011-04-21 US disclosed
US-20110039266-A1 FLOWCELL SYSTEMS FOR SINGLE MOLECULE DETECTION PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2011-02-17 US disclosed
US-20100273745-A1 POLYAMINES USEFUL AS ANTI-PARASITIC AND ANTI-CANCER THERAPEUTICS AND AS LYSINE-SPECIFIC DEMETHYLASE INHIBITORS THE JOHNS HOPKINS UNIVERSITY (US) 2010-10-28 US disclosed
US-20070208082-A1 POLYAMINES USEFUL AS ANTI-PARASITIC AND ANTI-CANCER THERAPEUTICS AND AS LYSINE-SPECIFIC DEMETHYLASE INHIBITORS JOHN HOPKINS UNIVERSITY (US) 2007-09-06 US disclosed
US-4647409-A Copper-phthalocyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1987-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208082-A1 POLYAMINES USEFUL AS ANTI-PARASITIC AND ANTI-CANCER THERAPEUTICS AND AS LYSINE-SPECIFIC DEMETHYLASE INHIBITORS KDM1A, JMJD6, SRM CHRM2 3888/4885TDP1 258/4885CYP2C9 4143/4885
US-20100273745-A1 POLYAMINES USEFUL AS ANTI-PARASITIC AND ANTI-CANCER THERAPEUTICS AND AS LYSINE-SPECIFIC DEMETHYLASE INHIBITORS KDM1A, JMJD6, SRM CHRM2 3888/4885TDP1 258/4885CYP2C9 4143/4885
US-20110092601-A1 LYSINE-SPECIFIC DEMETHYLASE INHIBITORS KDM4E, KDM3A, KDM2A CHRM2 3908/4885TDP1 158/4885CYP2C9 3448/4885
US-20110039266-A1 FLOWCELL SYSTEMS FOR SINGLE MOLECULE DETECTION POLN, POLQ, POLL CHRM2 3675/4885TDP1 1380/4885CYP2C9 3586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.