Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327398 | 0.84 | L3MBTL1 (0.49) | L3MBTL1HRH1KMT2AALDH1A1MEN1 | |
| SCHEMBL6598018 | 0.83 | SRD5A1 (0.39) | L3MBTL1EPHX2KMT2AALDH1A1NPSR1 | |
| SCHEMBL8419487 | 0.81 | SMN1; SMN2 (0.58) | HRH1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18687757 | 0.80 | L3MBTL1 (0.46) | L3MBTL1FABP5EPHX2KMT2AALDH1A1 | |
| SCHEMBL22589466 | 0.79 | KMT2A (0.42) | L3MBTL1FABP5EPHX2KMT2AALDH1A1 | |
| SCHEMBL29409631 | 0.79 | KMT2A (0.42) | L3MBTL1FABP5EPHX2KMT2AALDH1A1 | |
| SCHEMBL13327274 | 0.78 | POLB (0.52) | L3MBTL1FABP5EPHX2KMT2AALDH1A1 | |
| SCHEMBL22397770 | 0.78 | POLB (0.52) | L3MBTL1FABP5EPHX2KMT2AALDH1A1 | |
| SCHEMBL8419333 | 0.78 | GAA (0.57) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL693889 | 0.77 | L3MBTL1 (0.48) | L3MBTL1FABP5EPHX2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889025-A | Antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-30 | — | — | US | disclosed |