Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419352 | 0.99 | HPGD (0.45) | HPGDPTGER2PPARGPPARAPKM | |
| SCHEMBL8418028 | 0.96 | HPGD (0.47) | HPGDPTGER2PPARGPPARAPKM | |
| SCHEMBL8417489 | 0.91 | HPGD (0.44) | HPGDPTGER2PPARGPPARAPKM | |
| SCHEMBL8419575 | 0.90 | HPGD (0.46) | HPGDPTGER2PPARGPKMRPS6KB2 | |
| SCHEMBL8421783 | 0.90 | HPGD (0.45) | HPGDPTGER2PPARGPPARAPKM | |
| SCHEMBL8418191 | 0.89 | HPGD (0.44) | HPGDPTGER2PKMRPS6KB2APP | |
| SCHEMBL8418172 | 0.88 | HPGD (0.46) | HPGDPTGER2PPARGPPARAPKM | |
| SCHEMBL8421785 | 0.87 | HPGD (0.50) | HPGDPTGER2PPARGPPARARPS6KB2 | |
| SCHEMBL8419376 | 0.86 | HPGD (0.44) | HPGDPTGER2PPARGPPARAPKM | |
| SCHEMBL8421492 | 0.86 | HPGD (0.46) | HPGDPKMRPS6KB2APPTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |