Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MLYCD | O95822 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421209 | 0.98 | HPGD (0.43) | HPGDPTGER2RPS6KB2APPMLYCD | |
| SCHEMBL8421740 | 0.95 | HPGD (0.42) | HPGDPTGER2RPS6KB2APPMLYCD | |
| SCHEMBL8418172 | 0.93 | HPGD (0.46) | HPGDPTGER2RPS6KB2APPMLYCD | |
| SCHEMBL8419571 | 0.91 | HPGD (0.41) | HPGDPTGER2RPS6KB2APPMLYCD | |
| SCHEMBL8417489 | 0.91 | HPGD (0.44) | HPGDPTGER2RPS6KB2APPMLYCD | |
| SCHEMBL8417482 | 0.90 | HPGD (0.44) | HPGDRPS6KB2APPMLYCDTRPV1 | |
| SCHEMBL8421719 | 0.90 | HPGD (0.51) | HPGDPTGER2RPS6KB2APPMLYCD | |
| SCHEMBL8421783 | 0.90 | HPGD (0.45) | HPGDPTGER2RPS6KB2APPMLYCD | |
| SCHEMBL8418028 | 0.90 | HPGD (0.47) | HPGDPTGER2RPS6KB2APPMLYCD | |
| SCHEMBL8421565 | 0.89 | HPGD (0.43) | HPGDRPS6KB2APPMLYCDTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |