Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 5/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417408 | 0.81 | CES1 (0.48) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL28129843 | 0.79 | CES2 (0.59) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL5947952 | 0.72 | TSHR (0.52) | TDP1TSHRCYP3A4MAPTHSD17B10 | |
| SCHEMBL958533 | 0.70 | TDP1 (0.62) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL7567511 | 0.70 | TDP1 (0.62) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL147282 | 0.70 | CES2 (0.68) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL1415252 | 0.70 | TDP1 (0.62) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL2905276 | 0.70 | TDP1 (0.62) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL10497226 | 0.70 | TDP1 (0.62) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL27325956 | 0.70 | TDP1 (0.62) | TDP1CYP2C19TSHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939431-A | Naphthyridines which affect IL-4 and G-CSF | SCHERING CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |