Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421822 | 0.96 | HPGD (0.60) | HPGDPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL8421568 | 0.95 | HPGD (0.62) | HPGDPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL8421789 | 0.91 | HPGD (0.56) | HPGDPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL8419847 | 0.90 | HPGD (0.55) | HPGDPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL8419837 | 0.89 | HPGD (0.54) | HPGDPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL8421679 | 0.88 | HPGD (0.58) | HPGDPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL8419463 | 0.88 | HPGD (0.62) | HPGDPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL8418264 | 0.85 | HPGD (0.57) | HPGDPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL8421768 | 0.84 | HPGD (0.54) | HPGDPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL8418203 | 0.84 | HPGD (0.66) | HPGDPOLBTDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |