Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421822 | 0.87 | HPGD (0.60) | HPGDRPS6KB2TSHRTRPV1PKM | |
| SCHEMBL8421568 | 0.86 | HPGD (0.62) | HPGDRPS6KB2TSHRTRPV1PKM | |
| SCHEMBL8418260 | 0.85 | HPGD (0.57) | HPGDRPS6KB2TSHRTRPV1PKM | |
| SCHEMBL8419352 | 0.85 | HPGD (0.45) | HPGDRPS6KB2TSHRTRPV1PKM | |
| SCHEMBL8418028 | 0.84 | HPGD (0.47) | HPGDRPS6KB2TSHRTRPV1PKM | |
| SCHEMBL8418191 | 0.84 | HPGD (0.44) | HPGDRPS6KB2TRPV1PKMMIF | |
| SCHEMBL8418014 | 0.84 | HPGD (0.47) | HPGDRPS6KB2TRPV1PKMMIF | |
| SCHEMBL8421492 | 0.83 | HPGD (0.46) | HPGDRPS6KB2TSHRTRPV1PKM | |
| SCHEMBL8419575 | 0.83 | HPGD (0.46) | HPGDRPS6KB2TRPV1PKMALDH1A1 | |
| SCHEMBL2223317 | 0.80 | HPGD (0.64) | HPGDRPS6KB2ALDH1A1LMNAPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |