SCHEMBL8418366

SCHEMBL8418366

C=CCCCCC(C)CC=CCCCC(C)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683140 0.83 LMNA (0.40) TRPV1TRPM8TSHR
SCHEMBL6567837 0.81 TSHR (0.52) TRPV1TSHR
SCHEMBL8111294 0.80 TSHR (0.41) TRPV1TRPM8TSHR
SCHEMBL5078159 0.80 TSHR (0.41) TRPV1TRPM8TSHR
Ammonia Solution, Strong SCHEMBL3116437 0.80 TSHR (0.42) TSHR
SCHEMBL4824749 0.80 TSHR (0.43) TSHR
SCHEMBL28817765 0.78 TSHR (0.50) TRPV1TSHR
Ammonia Solution, Strong SCHEMBL3122842 0.78 TSHR (0.46) TSHR
Ammonia Solution, Strong SCHEMBL3124798 0.78 TSHR (0.46) TSHR
Ammonia Solution, Strong SCHEMBL3123530 0.78 TSHR (0.46) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5929297-A FORMING A MIXTURE OF DIMERS, TRIMERS AND OLIGOMERS BY CONTACTING AN ALPHA-OLEFIN WITH A CATALYST SYSTEM OF BORON TRIFLUORIDE, A PROTIC PROMOTER, AND A NITROGEN COMPOUND BEING AN AMIDE, UREA, IMIDE OR CARBAMATE BP AMOCO CORPORATION (US) 1999-07-27 US disclosed