Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768510 | 0.97 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL8422543 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL8420351 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL8768544 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL11382433 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL28942209 | 0.74 | CA12 (0.56) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL11582850 | 0.72 | CA12 (0.56) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL16197954 | 0.72 | MAPT (0.57) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL16651569 | 0.71 | KMT2A (0.53) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL7745405 | 0.71 | MAPT (0.58) | ALDH1A1KDM4EMAPTHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |