SCHEMBL84188

SCHEMBL84188

O=C(O)c1ccccc1-c1ccc2ccccc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.66
SLC6A4 P31645 1/20 0.66
SLC6A3 Q01959 1/20 0.66
ACMSD Q8TDX5 2/20 0.62
SOS1 Q07889 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
TSHR P16473 1/20 0.57
CYP2C19 P33261 1/20 0.57
HIF1A Q16665 1/20 0.57
GSTP1 P09211 1/20 0.55
HDAC4 P56524 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
MCL1 Q07820 1/20 0.51
CA12 O43570 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
FTO Q9C0B1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30610922 1.00 SLC6A2 (0.66) SLC6A2SLC6A4SLC6A3ACMSDSOS1
SCHEMBL29618929 1.00 SLC6A2 (0.66) SLC6A2SLC6A4SLC6A3ACMSDSOS1
Bromide SCHEMBL7032662 0.98 SLC6A2 (0.64) SLC6A2SLC6A4SLC6A3ACMSDSOS1
SCHEMBL1237964 0.89 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3ACMSDSOS1
SCHEMBL875658 0.87 SLC6A2 (0.68) SLC6A2SLC6A4SLC6A3ACMSDSOS1
SCHEMBL6883731 0.86 ACMSD (0.55) SLC6A2SLC6A4SLC6A3ACMSDSOS1
SCHEMBL27542885 0.85 ACMSD (0.62) SLC6A2SLC6A4SLC6A3ACMSDSOS1
SCHEMBL31513836 0.84 SOS1 (0.61) SLC6A2SLC6A4SLC6A3ACMSDSOS1
SCHEMBL15780703 0.84 KDM4E (0.64) SLC6A2SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL7787046 0.84 SLC6A2 (0.64) SLC6A2SLC6A4SLC6A3ACMSDSOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2479 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024218798-A1 AMINOPYRIDINE ANALOGUES AS 5-HYDROXYTRYPTAMINE RECEPTOR MODULATORS AND USES THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-10-24 WO claimed
EP-2346844-B1 SUBSTITUTED BENZFUROCHROMENES FOR THE PREVENTION AND TREATMENT OF BONE RELATED DISORDERS COUNCIL SCIENT IND RES (IN) 2017-09-20 EP claimed
CN-102264716-B For preventing and treat the substituted benzofuran of bone related disease chromene and related compound 科学与工业研究委员会 2016-08-31 CN claimed
EP-2864510-A1 METHOD FOR LEACHING ZINC SILICATE ORES Metaleach Limited (VG) 2015-04-29 EP claimed
WO-2014000021-A1 METHOD FOR LEACHING ZINC SILICATE ORES METALEACH LIMITED (VG) 2014-01-03 WO claimed
CN-102341402-A Thienopyridines as pharmacologically active agents COUNCIL SCIENT IND RES 2012-02-01 CN claimed
US-20120003273-A1 SUBSTITUTED BENZFUROCHROMENES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF BONE RELATED DISORDERS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETIES ACT (ACT XXI OF 1860)) (IN) 2012-01-05 US claimed
CN-102264716-A Substituted benzfurochromenes and related compounds for the prevention and treatment of bone related disorders 2011-11-30 CN claimed
EP-2346844-A1 SUBSTITUTED BENZFUROCHROMENES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF BONE RELATED DISORDERS Council Of Scientific & Industrial Research (IN) 2011-07-27 EP claimed
EP-1692101-B1 MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2011-07-06 EP claimed
CN-1839125-A (3R,4R)-trans-3,4-diarylchroman derivatives with estrogenic activity COUNCIL SCIENCE & INDUSTRY RES (IN) 2006-09-27 CN claimed
EP-1692101-A1 MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF Council of Scientific and Industrial Research (IN) 2006-08-23 EP claimed
CN-1802348-A Mercapto-phenyl-naphthyl-methane derivatives and preparation thereof COUNCIL SCIENT IND RES (IN) 2006-07-12 CN claimed
EP-1675843-A1 (3R, 4R) -TRANS-3,4-DIARYLCHROMAN DERIVATIVES WITH ESTROGENIC ACTIVITY Council of Scientific and Industrial Research (IN) 2006-07-05 EP claimed
WO-2005035517-A1 (3R, 4R)-TRANS-3,4-DIARYLCHROMAN DERIVATIVES WITH ESTROGENIC ACTIVITY COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-04-21 WO claimed
US-20050070597-A1 (3R, 4R)-trans-3, 4-diarylchroman derivatives and a method for the prevention and/or treatment of estrogen dependent diseases COUNSEL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-03-31 US claimed
US-20050054632-A1 Naphthyl compounds, intermediates, compositions, and methods of use BRYANT HENRY UHLMAN (US) 2005-03-10 US claimed
US-20040229869-A1 Novel mercaptophenyl naphthyl methane compounds and synthesis thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-11-18 US claimed
WO-2004087644-A1 MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-10-14 WO claimed
EP-0059983-A1 Substituted biphenyl compounds for use as a medicament THE WELLCOME FOUNDATION LIMITED (GB) 1982-09-15 EP claimed