SCHEMBL8418889

SCHEMBL8418889

CCn1cnc2cc3cc(Cl)ccc3cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.50
RAB9A P51151 8/20 0.50
KCNH2 Q12809 1/20 0.48
DPP4 P27487 1/20 0.43
DPP8 Q6V1X1 1/20 0.43
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
GAA P10253 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
KDM4E B2RXH2 4/20 0.40
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.39
PKM P14618 2/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTT P42858 2/20 0.38
FGFR1 P11362 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8418929 0.82 SMN1; SMN2 (0.53) NPC1RAB9AALDH1A1SMN1; SMN2GAA
SCHEMBL2564122 0.82 NPC1 (0.63) NPC1RAB9AKCNH2DPP4DPP8
SCHEMBL11331909 0.82 NPC1 (0.52) NPC1RAB9AKCNH2DPP4DPP8
SCHEMBL3298831 0.75 NPC1 (0.49) NPC1RAB9AKCNH2DPP4DPP8
SCHEMBL9482398 0.73 NPC1 (0.51) NPC1RAB9AKCNH2DPP4DPP8
SCHEMBL8506483 0.71 NPC1 (0.52) NPC1RAB9AKCNH2DPP4DPP8
SCHEMBL24462988 0.70 NPC1 (0.45) NPC1RAB9AKCNH2DPP4DPP8
SCHEMBL3303214 0.70 NPC1 (0.51) NPC1RAB9AKCNH2ALDH1A1SMN1; SMN2
SCHEMBL11351162 0.70 NPC1 (0.45) NPC1RAB9AKCNH2DPP4DPP8
SCHEMBL30391014 0.70 NPC1 (0.45) NPC1RAB9AKCNH2DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618492-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1999-09-22 EP disclosed
EP-0598241-B1 Lithographic printing material FUJI PHOTO FILM CO LTD (JP) 1998-02-04 EP disclosed
EP-0608777-B1 Processing of lithographic printing material FUJI PHOTO FILM CO LTD (JP) 1996-09-11 EP disclosed
US-5449596-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-12 US disclosed
US-5387483-A Developer containing silver halide solvent and hydroquinone; has pH up to 11.8 FUJI PHOTO FILM CO., LTD. (JP) 1995-02-07 US disclosed
EP-0618492-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-10-05 EP disclosed
EP-0608777-A1 Processing of lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-08-03 EP disclosed
EP-0601600-A2 Processing of lithographic printing material and developer used therein FUJI PHOTO FILM CO., LTD. (JP) 1994-06-15 EP disclosed
EP-0598241-A1 Lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-05-25 EP disclosed
US-5260183-A Cyanine dye, thiocyanate, triazolopyrimidine spectral sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-11-09 US disclosed
US-5035984-A Computer output images, nucleating agent FUJI PHOTO FILM CO., LTD. (JP) 1991-07-30 US disclosed
US-5015561-A Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
EP-0331185-A2 Silver halide photographic element for forming direct positive images and a method for forming said images FUJI PHOTO FILM CO., LTD. (JP) 1989-09-06 EP disclosed