SCHEMBL8418929

SCHEMBL8418929

CCn1cnc2cc3ccccc3cc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.53
ALDH1A1 P00352 4/20 0.53
NPC1 O15118 10/20 0.47
RAB9A P51151 9/20 0.47
KDM4E B2RXH2 7/20 0.47
MAPT P10636 5/20 0.47
TP53 P04637 3/20 0.47
GAA P10253 2/20 0.47
HTT P42858 2/20 0.47
KMT2A Q03164 2/20 0.47
PKM P14618 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
LMNA P02545 3/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8418889 0.82 NPC1 (0.50) SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E
SCHEMBL31357409 0.81 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1NPC1RAB9AHTT
SCHEMBL31357410 0.81 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1NPC1RAB9AHTT
SCHEMBL9677151 0.78 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E
SCHEMBL226221 0.77 TDP1 (0.70) SMN1; SMN2ALDH1A1HTTKMT2APKM
SCHEMBL4913688 0.77 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E
SCHEMBL12310197 0.76 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E
SCHEMBL7854588 0.76 LMNA (0.69) SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E
SCHEMBL10602253 0.75 CYP11B1 (0.53) SMN1; SMN2ALDH1A1NPC1RAB9AHTT
SCHEMBL9124464 0.75 CYP11B1 (0.53) SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618492-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1999-09-22 EP disclosed
US-5449596-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-12 US disclosed
EP-0618492-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-10-05 EP disclosed
US-5260183-A Cyanine dye, thiocyanate, triazolopyrimidine spectral sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-11-09 US disclosed