Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4642080 | 0.87 | ALDH1A1 (0.52) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL4642208 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL4644830 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL4642166 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL4641571 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL27601402 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL4644494 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL4641424 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL4646554 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL4645128 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDNPSR1VCAM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |