Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL5489282 | 0.93 | — | — | |
| Bicarbonate SCHEMBL6686501 | 0.93 | — | — | |
| Ethylene SCHEMBL7017604 | 0.93 | — | — | |
| Carbamic Acid SCHEMBL346428 | 0.85 | — | — | |
| SCHEMBL4395 | 0.84 | — | — | |
| SCHEMBL6328814 | 0.84 | LMNA (0.50) | ACHEALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL28555068 | 0.81 | — | — | |
| Bromide SCHEMBL5485388 | 0.81 | — | — | |
| Phosphine SCHEMBL3417770 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL989724 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719845-B1 | Water-base ink composition and process for producing the same | SEIKO EPSON CORP (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5693126-A | WATER RESISTANT PRINTS; LESS LIKELY TO CAUSE CLOGGING OF RECORDING HEAD | SEIKO EPSON CORPORATION (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0719845-A2 | Water-base ink composition and process for producing the same | SEIKO EPSON CORPORATION (JP) | 1996-07-03 | — | — | EP | disclosed |