Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421785 | 0.89 | HPGD (0.50) | HPGDPTGER2RPS6KB2PPARGTRPV1 | |
| SCHEMBL8419575 | 0.87 | HPGD (0.46) | HPGDPTGER2RPS6KB2PPARGTRPV1 | |
| SCHEMBL8418191 | 0.86 | HPGD (0.44) | HPGDPTGER2RPS6KB2TRPV1 | |
| SCHEMBL8417522 | 0.86 | HPGD (0.44) | HPGDPTGER2RPS6KB2TRPV1TSHR | |
| SCHEMBL8421492 | 0.86 | HPGD (0.46) | HPGDRPS6KB2TRPV1TSHR | |
| SCHEMBL8419468 | 0.85 | HPGD (0.44) | HPGDPTGER2RPS6KB2TRPV1 | |
| SCHEMBL8419344 | 0.85 | HPGD (0.45) | HPGDRPS6KB2TRPV1TSHR | |
| SCHEMBL8421543 | 0.83 | HPGD (0.44) | HPGDPTGER2RPS6KB2TRPV1TSHR | |
| SCHEMBL8417482 | 0.83 | HPGD (0.44) | HPGDRPS6KB2TRPV1TSHR | |
| SCHEMBL8419778 | 0.81 | HPGD (0.50) | HPGDRPS6KB2ALDH1A1LMNAPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |