Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20560206 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL6835277 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL19456057 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL8784768 | 0.78 | MAPT (0.47) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL8423522 | 0.78 | GAA (0.65) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL6099387 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1GAAHTT | |
| SCHEMBL1887376 | 0.76 | KMT2A (0.59) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL20560676 | 0.74 | MAPT (0.54) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL12139518 | 0.74 | MAPT (0.47) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL2755845 | 0.74 | MAPT (0.54) | ALDH1A1KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877324-A | ANTICHOLESTEROL AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-02 | — | — | US | disclosed |