SCHEMBL8419740

SCHEMBL8419740

CCCC(O)OC(=O)/C=C\C(=O)OCC

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.52
ATM Q13315 1/20 0.42
MAPT P10636 7/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
LMNA P02545 3/20 0.37
MDM2 Q00987 2/20 0.37
MDM4 O15151 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TTR P02766 1/20 0.35
DPP4 P27487 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8419742 1.00 HCAR2 (0.52) HCAR2ATMMAPTCA12CA1
SCHEMBL8676086 0.90 HCAR2 (0.40) HCAR2ATMMAPTNPSR1TSHR
SCHEMBL8676089 0.90 HCAR2 (0.40) HCAR2ATMMAPTNPSR1TSHR
SCHEMBL8416560 0.85 HCAR2 (0.55) HCAR2ATMMAPTCA12CA1
SCHEMBL8416554 0.85 HCAR2 (0.55) HCAR2ATMMAPTCA12CA1
SCHEMBL8417687 0.83 HCAR2 (0.50) HCAR2ATMMAPTCA1CA2
SCHEMBL8417691 0.83 HCAR2 (0.50) HCAR2ATMMAPTCA1CA2
SCHEMBL11654063 0.83 HCAR2 (0.53) HCAR2ATMMAPTALDH1A1TSHR
SCHEMBL10396797 0.83 HCAR2 (0.53) HCAR2ATMMAPTALDH1A1TSHR
SCHEMBL5336276 0.83 HCAR2 (0.53) HCAR2ATMMAPTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001892-A (A) UNSATURATED POLYESTER; (B) VINYL ETHER COMPONENT OF GIVEN FORMULA; AND (C) REACTIVE DILUENT COMPRISING AN UNSATURATED DIOIC ESTER OF GIVEN FORMULA, THE DILUENT LOWERS THE INITIAL APPLICATION VISCOSITY WITHOUT INCREASING CURE TIME PPG INDUSTRIES OHO, INC. (US) 1999-12-14 US disclosed
EP-0771331-B1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES INC (US) 1998-08-26 EP disclosed
EP-0771331-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1997-05-07 EP disclosed
WO-1996001283-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1996-01-18 WO disclosed