SCHEMBL8676089

SCHEMBL8676089

CCCC(O)OC(=O)C=CC(=O)OC(O)CCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.40
ATM Q13315 1/20 0.40
CHRM1 P11229 1/20 0.36
AKR1A1 P14550 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
DRD3 P35462 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
TSHR P16473 3/20 0.34
NPSR1 Q6W5P4 3/20 0.34
CYP3A4 P08684 2/20 0.34
NFKB1 P19838 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8676086 1.00 HCAR2 (0.40) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL8417687 0.92 HCAR2 (0.50) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL11654063 0.92 HCAR2 (0.53) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL10396797 0.92 HCAR2 (0.53) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL5336276 0.92 HCAR2 (0.53) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL8417691 0.92 HCAR2 (0.50) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL8419742 0.90 HCAR2 (0.52) HCAR2ATMTSHRNPSR1MAPT
SCHEMBL8419740 0.90 HCAR2 (0.52) HCAR2ATMTSHRNPSR1MAPT
SCHEMBL4613181 0.90 HCAR2 (0.32) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL4613185 0.90 HCAR2 (0.32) HCAR2ATMCHRM1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773541-A BLEND CONTAINING SURFACTANT IN AQUEOUS SOLUTION BASF AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed