SCHEMBL8419796

SCHEMBL8419796

CCC(O)OC(=O)/C=C\C(=O)OC(C)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.69
LMNA P02545 2/20 0.41
MDM4 O15151 1/20 0.41
MAPT P10636 1/20 0.41
MDM2 Q00987 1/20 0.41
LTB4R Q15722 4/20 0.40
LTB4R2 Q9NPC1 4/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
FFAR1 O14842 2/20 0.38
TRPA1 O75762 1/20 0.37
LPAR1 Q92633 1/20 0.37
LPAR3 Q9UBY5 1/20 0.37
MMP8 P22894 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
POLB P06746 1/20 0.36
KLK7 P49862 1/20 0.36
ADRA2A P08913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8419801 1.00 HCAR2 (0.69) HCAR2LMNAMDM4MAPTMDM2
SCHEMBL10339803 0.87 HCAR2 (0.89) HCAR2LMNAMDM4MAPTMDM2
SCHEMBL573375 0.87 HCAR2 (0.89) HCAR2LMNAMDM4MAPTMDM2
SCHEMBL573378 0.82 HCAR2 (1.00) HCAR2LMNAMDM4MAPTMDM2
SCHEMBL17868324 0.82 HCAR2 (1.00) HCAR2LMNAMDM4MAPTMDM2
SCHEMBL10339804 0.82 HCAR2 (1.00) HCAR2LMNAMDM4MAPTMDM2
SCHEMBL8417124 0.81 HCAR2 (0.68) HCAR2LMNAMDM4MAPTMDM2
SCHEMBL8417120 0.81 HCAR2 (0.68) HCAR2LMNAMDM4MAPTMDM2
SCHEMBL8872000 0.80 HCAR2 (0.76) HCAR2LMNAMDM4MAPTMDM2
SCHEMBL1845408 0.79 HCAR2 (0.75) HCAR2LTB4RLTB4R2KMT2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001892-A (A) UNSATURATED POLYESTER; (B) VINYL ETHER COMPONENT OF GIVEN FORMULA; AND (C) REACTIVE DILUENT COMPRISING AN UNSATURATED DIOIC ESTER OF GIVEN FORMULA, THE DILUENT LOWERS THE INITIAL APPLICATION VISCOSITY WITHOUT INCREASING CURE TIME PPG INDUSTRIES OHO, INC. (US) 1999-12-14 US disclosed
EP-0771331-B1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES INC (US) 1998-08-26 EP disclosed
EP-0771331-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1997-05-07 EP disclosed
WO-1996001283-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1996-01-18 WO disclosed