SCHEMBL8419797

SCHEMBL8419797

CC(OC(=O)/C=C\C(=O)OCCCO)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.64
MDM4 O15151 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
MDM2 Q00987 1/20 0.41
ALDH1A1 P00352 2/20 0.40
ATM Q13315 2/20 0.40
AKR1B10 O60218 3/20 0.39
AKR1B1 P15121 3/20 0.39
APP P05067 2/20 0.39
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
TP53 P04637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALOX5 P09917 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10339803 0.83 HCAR2 (0.89) HCAR2MDM4LMNAMAPTMDM2
SCHEMBL573375 0.83 HCAR2 (0.89) HCAR2MDM4LMNAMAPTMDM2
SCHEMBL8417120 0.80 HCAR2 (0.68) HCAR2MDM4LMNAMAPTMDM2
SCHEMBL8417124 0.80 HCAR2 (0.68) HCAR2MDM4LMNAMAPTMDM2
SCHEMBL573378 0.79 HCAR2 (1.00) HCAR2MDM4LMNAMAPTMDM2
SCHEMBL17868324 0.79 HCAR2 (1.00) HCAR2MDM4LMNAMAPTMDM2
SCHEMBL10339804 0.79 HCAR2 (1.00) HCAR2MDM4LMNAMAPTMDM2
SCHEMBL8641565 0.77 HCAR2 (0.52) HCAR2LMNAMAPTALDH1A1ATM
SCHEMBL8641575 0.77 HCAR2 (0.52) HCAR2LMNAMAPTALDH1A1ATM
SCHEMBL8872000 0.76 HCAR2 (0.76) HCAR2MDM4LMNAMAPTMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001892-A (A) UNSATURATED POLYESTER; (B) VINYL ETHER COMPONENT OF GIVEN FORMULA; AND (C) REACTIVE DILUENT COMPRISING AN UNSATURATED DIOIC ESTER OF GIVEN FORMULA, THE DILUENT LOWERS THE INITIAL APPLICATION VISCOSITY WITHOUT INCREASING CURE TIME PPG INDUSTRIES OHO, INC. (US) 1999-12-14 US disclosed
EP-0771331-B1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES INC (US) 1998-08-26 EP disclosed
EP-0771331-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1997-05-07 EP disclosed
WO-1996001283-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1996-01-18 WO disclosed