Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420249 | 1.00 | LMNA (0.47) | LMNAKDM4EPMP22ALOX15TP53 | |
| SCHEMBL8416806 | 1.00 | LMNA (0.47) | LMNAKDM4EPMP22ALOX15TP53 | |
| SCHEMBL8418228 | 1.00 | LMNA (0.47) | LMNAKDM4EPMP22ALOX15TP53 | |
| SCHEMBL8418406 | 1.00 | LMNA (0.47) | LMNAKDM4EPMP22ALOX15TP53 | |
| SCHEMBL8418258 | 1.00 | LMNA (0.47) | LMNAKDM4EPMP22ALOX15TP53 | |
| SCHEMBL8418234 | 1.00 | LMNA (0.47) | LMNAKDM4EPMP22ALOX15TP53 | |
| SCHEMBL8417887 | 1.00 | LMNA (0.47) | LMNAKDM4EPMP22ALOX15TP53 | |
| SCHEMBL8419747 | 1.00 | LMNA (0.47) | LMNAKDM4EPMP22ALOX15TP53 | |
| SCHEMBL6892074 | 1.00 | — | — | |
| SCHEMBL8419914 | 1.00 | LMNA (0.47) | LMNAKDM4EPMP22ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781801-B1 | Silica-filled rubber compositions containing dialkyleneamide polysulfides | GOODYEAR TIRE & RUBBER (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0781801-A1 | Silica-filled rubber compositions containing dialkyleneamide polysulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5641820-A | SULFUR VULCANIZABLE ELASTOMERS WITH COUPLING AGENTS, FOR TIRE TREADS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| US-4792628-A | ANTIOXIDANTS, ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-12-20 | — | — | US | disclosed |