Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 5/20 | 0.49 |
| ▸ | MMP8 | P22894 | 5/20 | 0.49 |
| ▸ | NMBR | P28336 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422131 | 0.88 | MMP9 (0.52) | MEN1KMT2AHCRTR1MMP9MMP8 | |
| SCHEMBL8418339 | 0.88 | MMP9 (0.52) | MEN1KMT2AHCRTR1MMP9MMP8 | |
| SCHEMBL31506426 | 0.80 | IL1RN (0.63) | MEN1KMT2AHCRTR1MMP9MMP8 | |
| SCHEMBL25139560 | 0.79 | MMP9 (0.70) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL21001592 | 0.79 | KMT2A (0.76) | MEN1KMT2AHCRTR1TACR1TP53 | |
| SCHEMBL21001593 | 0.79 | KMT2A (0.76) | MEN1KMT2AHCRTR1TACR1TP53 | |
| SCHEMBL8229351 | 0.79 | MEN1 (0.54) | MEN1KMT2AHCRTR1MMP9MMP8 | |
| SCHEMBL8221855 | 0.79 | MEN1 (0.53) | MEN1KMT2AHCRTR1MMP9MMP8 | |
| SCHEMBL8227146 | 0.79 | MEN1 (0.53) | MEN1KMT2AHCRTR1MMP9MMP8 | |
| SCHEMBL8221846 | 0.79 | MEN1 (0.53) | MEN1KMT2AHCRTR1MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335726-B2 | Lipopeptide stereoisomers, methods for preparing same and useful intermediates | CUBIST PHARMACEUTICALS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-20060223983-A1 | Lipopeptide stereoisomers, methods for preparing same and useful intermediates | CUBIST PHARMACEUTICALS, INC. | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223983-A1 | Lipopeptide stereoisomers, methods for preparing same and useful intermediates | NGLY1, LSS, NRDC | MEN1 1499/4885KMT2A 4489/4885HCRTR1 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.