Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3169044 | 0.87 | CYP4F2 (0.66) | CYP4F2CYP4A11MGLLBCHEFFAR1 | |
| SCHEMBL8420664 | 0.84 | KCNA3 (0.59) | KCNA3DRD2DRD4DRD3SLC2A1 | |
| SCHEMBL8767703 | 0.83 | CYP4F2 (0.61) | KCNA3DRD2DRD4DRD3CYP4F2 | |
| SCHEMBL20318731 | 0.83 | PPARA (0.58) | KCNA3KCNH2PPARGPPARA | |
| SCHEMBL20332570 | 0.83 | KCNA3 (0.53) | KCNA3DRD2DRD4DRD3CYP4F2 | |
| SCHEMBL8418971 | 0.83 | KCNA3 (0.53) | KCNA3DRD2DRD4DRD3CYP4F2 | |
| SCHEMBL416807 | 0.83 | FDFT1 (0.51) | FFAR1 | |
| SCHEMBL4516286 | 0.83 | KCNA3 (0.57) | KCNA3DRD2DRD4DRD3FFAR1 | |
| SCHEMBL11408226 | 0.80 | KCNA3 (0.76) | KCNA3DRD2DRD4DRD3HDAC3 | |
| SCHEMBL3165681 | 0.80 | PPARA (0.70) | FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |