SCHEMBL8767703

SCHEMBL8767703

OCCCc1cccc(OCCCCOc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.61
CYP4A11 Q02928 1/20 0.61
LTA4H P09960 1/20 0.57
EPHX2 P34913 1/20 0.57
KCNA3 P22001 1/20 0.53
ALDH1A1 P00352 1/20 0.53
RECQL P46063 1/20 0.53
DRD2 P14416 1/20 0.50
DRD4 P21917 1/20 0.50
DRD3 P35462 1/20 0.50
SLC2A1 P11166 1/20 0.49
POLB P06746 1/20 0.49
KCNH2 Q12809 1/20 0.49
FFAR1 O14842 3/20 0.49
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
F2 P00734 1/20 0.46
PLG P00747 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6001982 0.89 CYP4F2 (0.69) CYP4F2CYP4A11LTA4HEPHX2KCNA3
SCHEMBL23720120 0.89 CYP4F2 (0.59) CYP4F2CYP4A11LTA4HEPHX2ALDH1A1
SCHEMBL15016678 0.87 PPARA (0.59) CYP4F2CYP4A11KCNH2PPARGPPARA
SCHEMBL30458991 0.87 CYP4F2 (0.71) CYP4F2CYP4A11LTA4HEPHX2ALDH1A1
SCHEMBL9442321 0.87 CYP4F2 (0.61) CYP4F2CYP4A11LTA4HEPHX2KCNA3
SCHEMBL24041871 0.87 CYP4F2 (0.71) CYP4F2CYP4A11LTA4HEPHX2ALDH1A1
SCHEMBL3165628 0.87 CYP4F2 (0.81) CYP4F2CYP4A11LTA4HEPHX2ALDH1A1
SCHEMBL8499622 0.86 PPARA (0.62) KCNH2PPARGPPARA
SCHEMBL610023 0.85 CYP4F2 (0.51) CYP4F2CYP4A11LTA4HEPHX2POLB
SCHEMBL7215970 0.85 PPARA (0.54) CYP4F2CYP4A11POLBKCNH2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0791576-A2 Leukotriene antagonistic benzoic acid derivatives BAYER AG (DE) 1997-08-27 EP disclosed