Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CPT2 | P23786 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 3/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83786 | 0.84 | TSHR (0.55) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL28242184 | 0.82 | CYP2C19 (0.52) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL7156289 | 0.81 | HMGCR (0.42) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL7252624 | 0.78 | HMGCR (0.61) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL14573217 | 0.74 | TSHR (0.50) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL12914952 | 0.73 | HMGCR (0.55) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL233792 | 0.72 | CYP2C19 (0.52) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL7087814 | 0.72 | HMGCR (0.55) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| Ammonia Solution, Strong SCHEMBL25384796 | 0.72 | TSHR (0.47) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL4335360 | 0.70 | TSHR (0.46) | TSHRALDH1A1CPT2FFAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994445-A | PARTIALLY CRYSTALLINE POLY-M-XYLYLENE ADIPAMIDE; AND AN ALIPHATIC POLYAMIDE CONTAINING ORGANIC PARTICLES, INORGANIC PARTICLES OR BOTH WITH A PARTICLE DIAMETER OF LESS THAN 800 NM | WOLFF WALSRODE AG (DE) | 1999-11-30 | — | — | US | disclosed |