Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672035 | 0.88 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL20567296 | 0.88 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL28293188 | 0.88 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL28887112 | 0.88 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL3677555 | 0.88 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL7994628 | 0.88 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL6238997 | 0.88 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL7994715 | 0.86 | LMNA (0.48) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL11851525 | 0.85 | LMNA (0.37) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL18784680 | 0.82 | CES2 (0.41) | TSHRGPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4961707-A | COVERING WITH BIOABSORBABLE MATERIAL | UNIVERSITY OF FLORIDA (US) | 1990-10-09 | — | — | US | claimed |
| US-20180250007-A1 | TISSUE FASTENER AND METHODS FOR USING SAME | BONUTTI 2003 TRUST-A | 2018-09-06 | — | — | US | disclosed |
| US-9962162-B2 | Tissue fastener and methods for using same | P TECH, LLC (US) | 2018-05-08 | — | — | US | disclosed |
| US-20150245837-A1 | TISSUE FASTENER AND METHODS FOR USING SAME | P TECH, LLC | 2015-09-03 | — | — | US | disclosed |
| US-9060767-B2 | Tissue fastener and methods for using same | P TECH, LLC (US) | 2015-06-23 | — | — | US | disclosed |
| US-20090163938-A1 | TISSUE FASTENER AND METHODS FOR USING SAME | BONUTTI 2003 TRUST-A | 2009-06-25 | — | — | US | disclosed |
| US-7497864-B2 | Tissue fastener and methods for using same | MARCTEC, LLC. (US) | 2009-03-03 | — | — | US | disclosed |
| US-20040220591-A1 | Tissue fastener and methods for using same | BONUTTI 2003 TRUST-A | 2004-11-04 | — | — | US | disclosed |
| EP-0638392-B1 | Coated abrasives comprising a moisture cured polyurethane hot melt make coating | MINNESOTA MINING & MFG (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6039741-A | Method for surgical repair with hook-and-loop fastener | MEISLIN ROBERT J (US) | 2000-03-21 | — | — | US | disclosed |
| US-5994445-A | PARTIALLY CRYSTALLINE POLY-M-XYLYLENE ADIPAMIDE; AND AN ALIPHATIC POLYAMIDE CONTAINING ORGANIC PARTICLES, INORGANIC PARTICLES OR BOTH WITH A PARTICLE DIAMETER OF LESS THAN 800 NM | WOLFF WALSRODE AG (DE) | 1999-11-30 | — | — | US | disclosed |
| US-5906617-A | Surgical repair with hook-and-loop fastener | MEISLIN ROBERT J (US) | 1999-05-25 | — | — | US | disclosed |
| US-5595578-A | BACKING AND SUBSTRATE FOR ABRASIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0638392-A1 | Coated abrasives utilizing a moisture curable polyurethane hot melt make coating | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-15 | — | — | EP | disclosed |
| US-4961707-A | COVERING WITH BIOABSORBABLE MATERIAL | UNIVERSITY OF FLORIDA (US) | 1990-10-09 | — | — | US | disclosed |
| US-4457996-A | Tribo induction toner combination for carrierless development | XEROX CORPORATION (US) | 1984-07-03 | — | — | US | disclosed |
| US-4444487-A | Multiple-flash fuser | XEROX CORPORATION (US) | 1984-04-24 | — | — | US | disclosed |