Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 12/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.49 |
| ▸ | TTPA | P49638 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14948986 | 0.90 | PTPN1 (0.59) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL14948991 | 0.90 | PTPN1 (0.59) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL27553771 | 0.90 | PSEN1 (0.64) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL14948992 | 0.88 | PSEN1 (0.56) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL14948984 | 0.88 | PSEN1 (0.56) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL14490673 | 0.84 | GSTO1 (0.55) | PSEN1PTGS1PTGS2PTPN1GSTO1 | |
| SCHEMBL2059457 | 0.83 | PTGS1 (0.66) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL11701874 | 0.83 | PTGS1 (0.66) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL11705224 | 0.83 | PTGS1 (0.66) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7823401 | 0.83 | PSEN1 (0.57) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889045-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |