SCHEMBL8420935

SCHEMBL8420935

CCN(C=O)c1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.44
CYP3A4 P08684 1/20 0.42
ALDH1A1 P00352 2/20 0.42
ALDH3A1 P30838 1/20 0.42
ALDH1A3 P47895 1/20 0.42
CNR2 P34972 6/20 0.40
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
CNR1 P21554 4/20 0.38
MAPT P10636 1/20 0.36
CYP2A6 P11509 1/20 0.35
CYP2A13 Q16696 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28585831 0.81 HSD17B10 (0.38) HSD17B10CYP3A4ALDH1A1ALDH3A1ALDH1A3
SCHEMBL11317650 0.80 CYP2A6 (0.46) ALDH1A1ALDH3A1ALDH1A3CNR2CNR1
SCHEMBL17635948 0.78 ALDH1A1 (0.56) CYP3A4ALDH1A1ALDH3A1ALDH1A3KDM4E
SCHEMBL12643474 0.78 ESR1 (0.47) HSD17B10CYP3A4ALDH1A1ALDH3A1ALDH1A3
SCHEMBL31116625 0.77 TSHR (0.48) HSD17B10ALDH1A1ALDH3A1ALDH1A3ALOX15
SCHEMBL305842 0.77 TSHR (0.48) HSD17B10ALDH1A1ALDH3A1ALDH1A3ALOX15
SCHEMBL2094150 0.75 CNR2 (0.47) CNR2CNR1MAPT
SCHEMBL149576 0.74 ALDH1A1 (0.38) ALDH1A1ALDH3A1ALDH1A3CYP2A6CYP2A13
SCHEMBL12719218 0.74 ALDH1A1 (0.52) HSD17B10CYP3A4ALDH1A1ALDH3A1ALDH1A3
SCHEMBL11850274 0.74 HSD17B10 (0.61) HSD17B10CYP3A4ALDH1A1ALDH3A1ALDH1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5929297-A FORMING A MIXTURE OF DIMERS, TRIMERS AND OLIGOMERS BY CONTACTING AN ALPHA-OLEFIN WITH A CATALYST SYSTEM OF BORON TRIFLUORIDE, A PROTIC PROMOTER, AND A NITROGEN COMPOUND BEING AN AMIDE, UREA, IMIDE OR CARBAMATE BP AMOCO CORPORATION (US) 1999-07-27 US disclosed
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 US disclosed