Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13903612 | 0.84 | PTGDR2 (0.67) | L3MBTL1MAPK1POLBPABPC1APOBEC3A | |
| SCHEMBL13903614 | 0.83 | PTGDR2 (0.50) | L3MBTL1MAPK1POLBPABPC1APOBEC3A | |
| SCHEMBL5098541 | 0.81 | ALDH1A1 (0.56) | L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16559854 | 0.81 | ALDH1A1 (0.55) | L3MBTL1MAPK1POLBPABPC1APOBEC3A | |
| SCHEMBL4517104 | 0.79 | MEN1 (0.57) | MAPK1POLBPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL1853131 | 0.79 | PTGDR2 (0.53) | MAPK1POLBPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL1991699 | 0.79 | ALDH1A1 (0.50) | MAPK1POLBPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL1991697 | 0.79 | POLB (0.46) | L3MBTL1MAPK1POLBPABPC1APOBEC3A | |
| SCHEMBL27642138 | 0.78 | ALDH1A1 (0.52) | L3MBTL1POLBPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL1991262 | 0.77 | PTGDR2 (0.68) | L3MBTL1MAPK1POLBPABPC1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |