SCHEMBL8422167

SCHEMBL8422167

O=C1OC2CCCCCCCCCCC/C=C\12

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
HIF1A Q16665 1/20 0.32
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1301127 1.00 MAPT (0.33) MAPTHIF1AHSD11B1
SCHEMBL997027 1.00 MAPT (0.33) MAPTHIF1AHSD11B1
SCHEMBL1515669 0.88
SCHEMBL11286745 0.83
SCHEMBL1515635 0.75 MKNK2 (0.32)
SCHEMBL29475259 0.70
SCHEMBL13585913 0.67 KDM1A (0.38) HIF1AHSD11B1
SCHEMBL11076742 0.66 MAPT (0.37) MAPTHIF1AHSD11B1
SCHEMBL11076741 0.66 MAPT (0.37) MAPTHIF1AHSD11B1
SCHEMBL3397911 0.61 MAPT (0.62) MAPTHIF1AHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6008185-A EXCELLENT OLFACTORY PROPERTIES; PERFUMES HAVING A MUSKY SCENT HAARMANN & REIMER GMBH (DE) 1999-12-28 US disclosed
EP-0862911-A2 Use of macrocyclic lactones as fragrances HAARMANN & REIMER GMBH (DE) 1998-09-09 EP disclosed