Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421656 | 0.95 | KDM1A (0.42) | KDM1AMALT1KAT6AAURKAPTGS2 | |
| SCHEMBL8421776 | 0.91 | KDM1A (0.47) | KDM1AMALT1KAT6AAURKAPTGS2 | |
| SCHEMBL8420731 | 0.90 | KDM1A (0.43) | KDM1AMALT1AURKAPTGS2MAOA | |
| SCHEMBL8422266 | 0.90 | KDM1A (0.43) | KDM1AMALT1AURKAPTGS2MAOA | |
| SCHEMBL8641119 | 0.89 | AURKA (0.46) | KDM1AMALT1KAT6AAURKAPTGS2 | |
| SCHEMBL8420734 | 0.89 | MALT1 (0.43) | KDM1AMALT1KAT6AAURKAMAOA | |
| SCHEMBL8420739 | 0.89 | MALT1 (0.40) | KDM1AMALT1KAT6AAURKAPTGS2 | |
| SCHEMBL8421082 | 0.88 | MALT1 (0.39) | KDM1AMALT1KAT6AAURKANAT1 | |
| SCHEMBL8423817 | 0.87 | MAPT (0.46) | KDM1AMALT1AURKAPTGS2MAOA | |
| SCHEMBL8424007 | 0.87 | MAPT (0.46) | KDM1AMALT1AURKAPTGS2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |