Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421953 | 0.96 | MALT1 (0.43) | MALT1KAT6AKDM1AMAOAAURKA | |
| SCHEMBL8420739 | 0.91 | MALT1 (0.40) | MALT1KAT6AKDM1AMAOAAURKA | |
| SCHEMBL8420103 | 0.90 | PTGS2 (0.45) | MALT1KAT6AKDM1AMAOAAURKA | |
| SCHEMBL8420731 | 0.90 | KDM1A (0.43) | MALT1KDM1AMAOAAURKACYP1A2 | |
| SCHEMBL8422266 | 0.90 | KDM1A (0.43) | MALT1KDM1AMAOAAURKACYP1A2 | |
| SCHEMBL8641119 | 0.90 | AURKA (0.46) | MALT1KAT6AKDM1AMAOAAURKA | |
| SCHEMBL8422378 | 0.89 | KDM1A (0.40) | MALT1KAT6AKDM1AMAOAAURKA | |
| SCHEMBL8421776 | 0.89 | KDM1A (0.47) | MALT1KAT6AKDM1AMAOAAURKA | |
| SCHEMBL8423597 | 0.87 | KAT6A (0.42) | MALT1KAT6AKDM1AMAOAAURKA | |
| SCHEMBL8421734 | 0.87 | KDM1A (0.43) | MALT1KAT6AKDM1AMAOAAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |