Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82993 | 1.00 | ACACB (0.33) | ACACBSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL82991 | 1.00 | ACACB (0.33) | ACACBSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL84225 | 1.00 | ACACB (0.33) | ACACBSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL82992 | 1.00 | ACACB (0.33) | ACACBSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL83202 | 0.87 | SMN1; SMN2 (0.44) | ACACBSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL12580713 | 0.86 | SMN1; SMN2 (0.44) | ACACBSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL84487 | 0.86 | SMN1; SMN2 (0.44) | ACACBSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL82296 | 0.85 | JAK3 (0.33) | ACACBSMN1; SMN2LMNAHTTNCOA3 | |
| SCHEMBL82295 | 0.85 | JAK3 (0.33) | ACACBSMN1; SMN2LMNAHTTNCOA3 | |
| SCHEMBL83129 | 0.83 | JAK3 (0.44) | ACACBALDH1A1LMNAJAK3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129526-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-7973028-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7968537-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7928110-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7732448-B2 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20100036117-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090209518-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090209519-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090203674-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20060199800-A1 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199800-A1 | Pyrimidine compounds and pests controlling composition containing the same | C5, C1S, TYMS | ACACB 1246/4885SMN1; SMN2 2436/4885MEN1 3344/4885 |
| US-20090203674-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | ACACB 1331/4885SMN1; SMN2 2743/4885MEN1 2686/4885 |
| US-20090209518-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | ACACB 1391/4885SMN1; SMN2 2689/4885MEN1 2630/4885 |
| US-20100036117-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, CCNB3 | ACACB 1652/4885SMN1; SMN2 1891/4885MEN1 1686/4885 |
| US-20090209519-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | ACACB 1548/4885SMN1; SMN2 2567/4885MEN1 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.