Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422670 | 1.00 | GPR52 (0.51) | GPR52MAPTCCNCCDK8CYP1A2 | |
| SCHEMBL6777641 | 0.86 | CCNC (0.48) | MAPTCCNCCDK8CYP1A2CYP2A6 | |
| SCHEMBL6777638 | 0.86 | CCNC (0.48) | MAPTCCNCCDK8CYP1A2CYP2A6 | |
| SCHEMBL1268421 | 0.83 | MAPT (0.62) | GPR52MAPT | |
| SCHEMBL1268422 | 0.83 | MAPT (0.62) | GPR52MAPT | |
| SCHEMBL8424521 | 0.82 | MAPT (0.48) | GPR52MAPTTTRDPP4 | |
| SCHEMBL8424519 | 0.82 | MAPT (0.48) | GPR52MAPTTTRDPP4 | |
| SCHEMBL27310629 | 0.80 | MAPT (0.59) | GPR52MAPT | |
| SCHEMBL27310628 | 0.80 | MAPT (0.59) | GPR52MAPT | |
| SCHEMBL27311627 | 0.80 | MAPT (0.59) | GPR52MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949238-A1 | SUBSTITUTED PROPIONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |