Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421109 | 0.89 | PTGS2 (0.55) | PTGS2PTGS1CA1CA2CA7 | |
| SCHEMBL8423199 | 0.86 | PTGS2 (0.48) | PTGS2PTGS1CA1CA2CA7 | |
| SCHEMBL8423260 | 0.86 | SGK1 (0.42) | PTGS2PTGS1CA9MEN1KMT2A | |
| SCHEMBL8099213 | 0.82 | PTGS2 (0.67) | PTGS2PTGS1CA1CA2CA7 | |
| SCHEMBL8423058 | 0.80 | PTGS2 (0.50) | PTGS2PTGS1CA1CA2CA7 | |
| SCHEMBL8419909 | 0.80 | PTGS2 (0.46) | PTGS2PTGS1CA1CA2CA7 | |
| SCHEMBL8421302 | 0.77 | PTGS2 (0.44) | PTGS2PTGS1CA1CA2CA7 | |
| SCHEMBL8424482 | 0.77 | PTGS2 (0.47) | PTGS2PTGS1CA1CA2CA7 | |
| SCHEMBL8419785 | 0.76 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL8423389 | 0.76 | PTGS2 (0.46) | PTGS2PTGS1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |