Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421259 | 0.93 | KDM4E (0.52) | KDM4EPOLBACLYPIK3CGSTAT3 | |
| SCHEMBL8419850 | 0.92 | ACLY (0.57) | KDM4EACLYPIK3CGSTAT3TUBB4A | |
| SCHEMBL8423384 | 0.92 | STAT3 (0.54) | KDM4EACLYPIK3CGSTAT3TUBB4A | |
| SCHEMBL8423073 | 0.91 | STAT3 (0.48) | KDM4EACLYPIK3CGSTAT3TUBB4A | |
| SCHEMBL8419328 | 0.91 | KDM4E (0.53) | KDM4EPOLBACLYPIK3CGSTAT3 | |
| SCHEMBL8423385 | 0.91 | KDM4E (0.47) | KDM4EACLYPIK3CGSTAT3TUBB4A | |
| SCHEMBL8421277 | 0.91 | KDM4E (0.47) | KDM4EPOLBACLYPIK3CGSTAT3 | |
| SCHEMBL8421240 | 0.90 | KDM4E (0.47) | KDM4EPOLBACLYPIK3CGSTAT3 | |
| SCHEMBL8421055 | 0.90 | KDM4E (0.47) | KDM4EPOLBACLYPIK3CGSTAT3 | |
| SCHEMBL8419960 | 0.90 | KDM4E (0.47) | KDM4EACLYPIK3CGSTAT3TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5686470-A | 2, 3-substituted pyridines for the treatment of inflammation | WEIER RICHARD M (US) | 1997-11-11 | — | — | US | disclosed |