Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600063 | 0.94 | TSHR (0.51) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL21300657 | 0.94 | TSHR (0.51) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL16599972 | 0.94 | TSHR (0.51) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL16407297 | 0.91 | TSHR (0.49) | TSHRTHRBKDM4EMEN1KMT2A | |
| SCHEMBL22016787 | 0.87 | TSHR (0.45) | TSHRTHRBKDM4E | |
| SCHEMBL27054834 | 0.86 | TSHR (0.47) | TSHRTHRBKDM4E | |
| SCHEMBL19523486 | 0.85 | TSHR (0.44) | TSHRTHRBKDM4E | |
| SCHEMBL5280138 | 0.84 | TSHR (0.49) | TSHRTHRBKDM4E | |
| SCHEMBL9706996 | 0.84 | TSHR (0.49) | TSHRTHRBKDM4E | |
| SCHEMBL8434514 | 0.84 | TSHR (0.42) | TSHRTHRBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858524-A | HYDROXYAMINE-CONTAINING ACRYLATE PACKAGING LAMINATES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-01-12 | — | — | US | claimed |
| EP-0841157-A2 | Flexible laminates bonded with water-based laminating ink vehicles and laminating adhesives | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| US-5858524-A | HYDROXYAMINE-CONTAINING ACRYLATE PACKAGING LAMINATES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0841157-A2 | Flexible laminates bonded with water-based laminating ink vehicles and laminating adhesives | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-05-13 | — | — | EP | disclosed |