Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706996 | 0.87 | TSHR (0.49) | TSHRALDH1A1THRBKDM4EADRB2 | |
| SCHEMBL16407297 | 0.87 | TSHR (0.49) | TSHRTHRBKDM4EADRB2ADRB1 | |
| SCHEMBL16573834 | 0.86 | TSHR (0.47) | TSHRALDH1A1THRBKDM4EADRB2 | |
| SCHEMBL19523487 | 0.84 | TSHR (0.46) | TSHRALDH1A1THRBKDM4EADRB2 | |
| SCHEMBL13311776 | 0.84 | TSHR (0.46) | TSHRALDH1A1THRBKDM4EADRB2 | |
| SCHEMBL8423288 | 0.84 | TSHR (0.46) | TSHRTHRBKDM4E | |
| SCHEMBL9685168 | 0.84 | THRB (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL12621226 | 0.83 | KDM4E (0.53) | TSHRALDH1A1THRBKDM4EADRB2 | |
| SCHEMBL22016787 | 0.83 | TSHR (0.45) | TSHRALDH1A1THRBKDM4EADRB2 | |
| SCHEMBL14932557 | 0.83 | TSHR (0.45) | TSHRALDH1A1THRBADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2764065-B1 | SACRIFICIAL ADHESIVE COATINGS | ROCHAL IND LLC (US) | 2017-03-22 | — | — | EP | claimed |
| CN-102713744-B | Silicon-containing liquid crystal aligning agent, liquid crystal orientation film and liquid crystal display cells | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-12-02 | — | — | CN | disclosed |
| CN-102713744-A | Silicon-containing liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element | NISSAN CHEMICAL IND LTD | 2012-10-03 | — | — | CN | disclosed |
| EP-1433814-B1 | CURABLE COMPOSITION, CURED ARTICLE OBTAINED THEREFROM, AND PHOTOCHROMIC OPTICAL MATERIAL AND PROCESS FOR PRODUCING THE SAME | TOKUYAMA CORP (JP) | 2007-12-19 | — | — | EP | disclosed |