Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CTSV | O60911 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423567 | 1.00 | MAPT (0.60) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL27629995 | 0.94 | MAPT (0.60) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL30203403 | 0.92 | ALDH1A1 (0.56) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL1403472 | 0.92 | ALDH1A1 (0.56) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| Methane SCHEMBL27588822 | 0.90 | ALDH1A1 (0.54) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL25336874 | 0.87 | ALDH1A1 (0.52) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL16951683 | 0.87 | ALDH1A1 (0.52) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL6592607 | 0.87 | MAPT (0.54) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL9324004 | 0.87 | ALDH1A1 (0.60) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL11547738 | 0.86 | ALDH1A1 (0.51) | MAPTALDH1A1TDP1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950774-B | Protein quantitative marking reagent and preparation method and application thereof | 北京大学 | 2021-04-13 | — | — | CN | disclosed |
| CN-110950774-A | Protein quantitative marking reagent and preparation method and application thereof | 北京大学 | 2020-04-03 | — | — | CN | disclosed |
| CN-100522171-C | 1-Benzoylpiperazine derivatives as glycine uptake inhibitors for the treatment of psychosis | HOFFMANN LA ROCHE (CH) | 2009-08-05 | — | — | CN | disclosed |
| CN-100443464-C | AB type dibasic aminoacid monomer containing hydroxy group and its preparation method | UNIV SICHUAN (CN) | 2008-12-17 | — | — | CN | disclosed |
| CN-1878554-A | 1-benzoyl-piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses | HOFFMANN LA ROCHE (CH) | 2006-12-13 | — | — | CN | disclosed |
| CN-1865225-A | AB type dibasic aminoacid monomer containing hydroxy group and its preparation method | UNIV SICHUAN (CN) | 2006-11-22 | — | — | CN | disclosed |
| US-6005010-A | CARDIOVASCULAR DISORDERS, ANTIARRHYTHMIA AGENTS AND ANTIISCHEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |