⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dithioerythriol SCHEMBL15611744 | 0.97 | — | — | |
| Dithioerythriol SCHEMBL78922 | 0.97 | — | — | |
| Dithioerythriol SCHEMBL10602 | 0.97 | — | — | |
| Dithioerythriol SCHEMBL9773254 | 0.94 | — | — | |
| Dithioerythriol SCHEMBL3422787 | 0.94 | — | — | |
| Dithioerythriol SCHEMBL3380453 | 0.89 | LMNA (0.39) | — | |
| Dithioerythriol SCHEMBL16566794 | 0.83 | PDE4A (0.37) | — | |
| Dithioerythriol SCHEMBL7523387 | 0.83 | PDE4A (0.37) | — | |
| Dithioerythriol SCHEMBL9109286 | 0.83 | PDE4A (0.37) | — | |
| Dithioerythriol SCHEMBL7113064 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965415-A | CREATING HYBRID GENES BY TRANSFORMING BACTERIA CELLS HAVING A DEFECTIVE MISMATCH REPAIR SYSTEM OR TRANSITORILY DEACTIVATED WITH TWO HOMOLOGOUS DNA SEQUENCES HAVING MISMATCHES, SCREENING CELLS WHICH HAVE UNDERGONE STABLE RECOMBINATION | MIXIS FRANCE, S.A. (FR) | 1999-10-12 | — | — | US | disclosed |
| US-5912119-A | IN SITU MUTATION METHOD FOR INTERGENERIC AND/OR INTERSPECIFIC RECOMBINATION; TRANSDUCTING NUCLEIC ACID INTO CELLS; FUSING WITH CELLS OF A SECOND SPECIES WITH A DEFECTIVE OR INACTIVE ENZYMATIC MISMATCH REPAIR SYSTEMS CREATING HYBRID GENES | MIXIS FRANCE, S.A. (FR) | 1999-06-15 | — | — | US | disclosed |