Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424348 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HTR2CHTR3EHTR3BHTR1D | |
| SCHEMBL8428299 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HTR2CHTR3EHTR3BHTR1D | |
| Hydrochloric Acid SCHEMBL8425578 | 0.82 | MAPT (0.43) | ALDH1A1HTR2CHTR3EHTR3BHTR1D | |
| SCHEMBL8010813 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HTR2CHTR3EHTR3BHTR1D | |
| SCHEMBL9064671 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HTR2CHTR3EHTR3BHTR1D | |
| SCHEMBL14369671 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HTR2CHTR3EHTR3BHTR1D | |
| SCHEMBL8424321 | 0.74 | NOTUM (0.41) | ALDH1A1NOTUMLMNASMN1; SMN2MEN1 | |
| SCHEMBL8425467 | 0.74 | NOTUM (0.41) | ALDH1A1NOTUMLMNASMN1; SMN2MEN1 | |
| SCHEMBL8423614 | 0.73 | NOTUM (0.40) | ALDH1A1NOTUMLMNASMN1; SMN2MEN1 | |
| SCHEMBL8428186 | 0.73 | NOTUM (0.40) | ALDH1A1NOTUMLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636616-B1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-5484933-A | Process for production of fluoroalkane carboxamide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0636616-A1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-01 | — | — | EP | disclosed |