Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872899 | 1.00 | TSHR (0.48) | TSHRALDH1A1DNM1MEN1POLB | |
| SCHEMBL20529604 | 0.83 | TSHR (0.41) | TSHRALDH1A1MEN1POLBKMT2A | |
| SCHEMBL11130605 | 0.82 | TSHR (0.35) | TSHRALDH1A1MEN1POLBKMT2A | |
| SCHEMBL11115491 | 0.76 | TSHR (0.34) | TSHRALDH1A1MEN1POLBKMT2A | |
| SCHEMBL27648624 | 0.75 | DNM1 (0.48) | TSHRALDH1A1DNM1THRBCA12 | |
| SCHEMBL9476510 | 0.75 | DNM1 (0.48) | TSHRALDH1A1DNM1THRBCA12 | |
| SCHEMBL28758717 | 0.75 | DNM1 (0.48) | TSHRALDH1A1DNM1THRBCA12 | |
| SCHEMBL10720718 | 0.75 | TSHR (0.40) | TSHRALDH1A1DNM1MEN1POLB | |
| Dymanthine SCHEMBL23633191 | 0.73 | DNM1 (0.60) | TSHRALDH1A1DNM1MEN1POLB | |
| SCHEMBL6679948 | 0.73 | DNM1 (0.46) | TSHRALDH1A1DNM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454622-B1 | Alkenyl substituted stabilizers | CIBA GEIGY AG (CH) | 1999-10-13 | — | — | EP | claimed |
| EP-0454622-A1 | Alkenyl substituted stabilizers | CIBA-GEIGY AG (CH) | 1991-10-30 | — | — | EP | claimed |
| US-5045583-A | O-alkenyl substituted hydroxylamine stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-09-03 | — | — | US | claimed |
| EP-0454622-B1 | Alkenyl substituted stabilizers | CIBA GEIGY AG (CH) | 1999-10-13 | — | — | EP | disclosed |
| EP-0454622-A1 | Alkenyl substituted stabilizers | CIBA-GEIGY AG (CH) | 1991-10-30 | — | — | EP | disclosed |
| US-5045583-A | O-alkenyl substituted hydroxylamine stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |