Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051251 | 0.90 | FOLH1 (0.43) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7052340 | 0.79 | FOLH1 (0.41) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7052258 | 0.78 | FOLH1 (0.40) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7053258 | 0.71 | FOLH1 (0.44) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7607842 | 0.70 | FOLH1 (0.62) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8060048 | 0.64 | FOLH1 (1.00) | FOLH1GRM3NAALAD2 | |
| SCHEMBL28863951 | 0.63 | FOLH1 (0.36) | FOLH1 | |
| SCHEMBL8063534 | 0.62 | FOLH1 (0.58) | FOLH1GRM3NAALAD2 | |
| SCHEMBL19773237 | 0.62 | GRM8 (0.32) | FOLH1 | |
| SCHEMBL14036443 | 0.62 | SIGMAR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949922-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING COMPULSIVE DISORDERS USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998013044-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING COMPULSIVE DISORDERS USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | disclosed |