Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KAT8 | Q9H7Z6 | 9/20 | 0.53 |
| ▸ | EP300 | Q09472 | 7/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423941 | 1.00 | KMT2A (0.54) | KMT2AMEN1KAT8EP300FNTA | |
| SCHEMBL8008711 | 0.94 | KAT8 (0.59) | KMT2AMEN1KAT8EP300FNTA | |
| SCHEMBL6947870 | 0.94 | KAT8 (0.59) | KMT2AMEN1KAT8EP300FNTA | |
| SCHEMBL8427624 | 0.87 | FNTA (0.51) | KMT2AMEN1KAT8EP300FNTA | |
| SCHEMBL8427626 | 0.87 | FNTA (0.51) | KMT2AMEN1KAT8EP300FNTA | |
| SCHEMBL8425624 | 0.86 | FNTA (0.49) | KMT2AMEN1KAT8EP300FNTA | |
| SCHEMBL8425621 | 0.86 | FNTA (0.49) | KMT2AMEN1KAT8EP300FNTA | |
| SCHEMBL8425816 | 0.85 | MEN1 (0.48) | KMT2AMEN1KAT8EP300FNTA | |
| SCHEMBL8425818 | 0.85 | MEN1 (0.48) | KMT2AMEN1KAT8EP300FNTA | |
| SCHEMBL8425491 | 0.85 | GAA (0.43) | KMT2AMEN1GAAAMY1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |