Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL3360754 | 0.96 | KDM4E (0.54) | GPR119KDM4EPKM | |
| SCHEMBL6399672 | 0.93 | GPR119 (0.45) | GPR119KDM4EPKM | |
| SCHEMBL5192061 | 0.89 | GPR119 (0.51) | GPR119HPGDKDM4EPKM | |
| SCHEMBL5192065 | 0.88 | KDM4E (0.51) | GPR119HPGDKDM4EPKM | |
| SCHEMBL4096002 | 0.87 | GPR119 (0.50) | GPR119HPGDKDM4EPKM | |
| SCHEMBL6156324 | 0.87 | HPGD (0.58) | GPR119HPGDKDM4EPKM | |
| SCHEMBL27417726 | 0.86 | HPGD (0.50) | GPR119HPGDKDM4EPKM | |
| SCHEMBL27271717 | 0.86 | HPGD (0.45) | GPR119HPGDKDM4EPKM | |
| SCHEMBL6150245 | 0.85 | GPR119 (0.51) | GPR119HPGDKDM4EPKM | |
| SCHEMBL6156540 | 0.85 | GPR119 (0.53) | GPR119HPGDKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112692-A1 | CASITAS B-LINEAGE LYMPHOMA PROTOONCOGENE B (CBL-B) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| US-5965578-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-10-12 | — | — | US | disclosed |
| CN-1022244-C | Tetrazole excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 1993-09-29 | — | — | CN | disclosed |
| CN-1035114-A | TETRAZOLE EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1989-08-30 | — | — | CN | disclosed |