Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424070 | 1.00 | KMT2A (0.43) | KMT2AMEN1POLBGAAAMY1A | |
| SCHEMBL6949812 | 0.95 | KMT2A (0.47) | KMT2AMEN1POLBGAAAMY1A | |
| SCHEMBL6949810 | 0.95 | KMT2A (0.47) | KMT2AMEN1POLBGAAAMY1A | |
| SCHEMBL8428063 | 0.91 | PTGS2 (0.45) | KMT2AMEN1POLBGAAAMY1A | |
| SCHEMBL8428064 | 0.91 | PTGS2 (0.45) | KMT2AMEN1POLBGAAAMY1A | |
| SCHEMBL6949544 | 0.87 | PTGS2 (0.47) | KMT2AMEN1POLBGAAAMY1A | |
| SCHEMBL6949542 | 0.87 | PTGS2 (0.47) | KMT2AMEN1POLBGAAAMY1A | |
| SCHEMBL8015654 | 0.86 | KAT8 (0.41) | KMT2AMEN1PTGS2L3MBTL1ALDH1A1 | |
| SCHEMBL8015657 | 0.86 | KAT8 (0.41) | KMT2AMEN1PTGS2L3MBTL1ALDH1A1 | |
| SCHEMBL6947265 | 0.83 | KAT8 (0.42) | KMT2AMEN1POLBGAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |